Posts Tagged ‘GMO’

Will Non-GMO Foods Be Less Nutritious?

Written by Dr. Steve Chaney on . Posted in Food and Health, Issues

The Unintended Consequences of the Proposed Non-GMO Labeling Laws

Author: Dr. Stephen Chaney

CerealPost Foods recently announced that their Grape Nuts cereal will be completely non-GMO. General Foods followed suit by announcing that their Original Cheerios will also be non-GMO. That’s good news, right?

Maybe, but it turns out that the new non-GMO Grape Nuts will no longer contain vitamins A, D, B12 or riboflavin, and the amount of riboflavin in a serving of Cheerios decreased from 25% of the daily recommended value (DV) to 2% of the DV.

The cereal manufacturers claim that their new cereals are more wholesome, but one nutrition expert said “The new products are arguably less healthy given their lower vitamin content.”

I’ve never been one to claim that throwing a few vitamins into a serving of cereal turns it into a nutrition powerhouse, but the decreased vitamin content of the new non-GMO cereals does raise a few questions.

  • Why were the vitamins removed?
  • Did it have anything to do with the cereals being non-GMO?
  • Does this mean that the non-GMO processed foods of the future will be less nutritious than the foods they replace?

The cereal manufacturers were mum when asked these questions, so we will need to rely on some scientific sleuthing and a bit of intuition to get the answers.

The Flaw in The Proposed Non-GMO Labeling Laws

I first discussed this topic a few months ago in a “Health Tips From The Professor” article titled “When is GMO Non-GMO?” I received a lot of irate comments from people who take every word on the non-GMO websites and videos as the gospel truth. (The professor has never been one to shy away from controversy when he sees claims that aren’t based on good science.)

However, I think my article was misunderstood by some of my readers, so let me review my conclusions briefly:

  • There are definitely environmental concerns around the widespread use of GM crops – especially those that allow heavy pesticide and herbicide usage.
  • There are potential health concerns related to the consumption of unprocessed GM foods and proteins derived from GM foods – although those heath concerns have been blown way out of proportion in the media.

If the proposed Non-GMO labeling laws stopped there, they would be scientifically justified. But they go one step further by requiring that processed foods labeled as non-GMO cannot contain any ingredient obtained from a GM source. There is no scientific justification for this.

  • Nutrients (sugars, oils & vitamins) derived from GM sources are chemically and biologically indistinguishable from those same nutrients derived from non-GMO sources.

The intentions of the proposed non-GMO labeling laws are good, but whenever you go beyond what good science supports there are often unintended consequences – such as the vitamin-depleted non-GMO cereals that the food manufacturers have just announced.

Will Non-GMO Foods Be Less Nutritious?

Non-GMOTo understand the answer to that question, let’s look at what probably happened to the vitamins in the non-GMO cereals.

In today’s world many vitamins are purified from genetically modified microorganisms – bacteria & yeast that have been modified to overproduce certain vitamins. In evaluating the significance of that statement, here are a few facts to consider:

1)     We have gotten vitamins from these sources for many years.

    • B vitamins have been obtained from yeast for at least a hundred years.
    • A significant portion of the vitamins we absorb on a daily basis are made by bacteria in our gut.

2)     The only difference today is that these microorganisms have been genetically modified to overproduce the vitamins.

3)     These are naturally sourced vitamins.

  • The microorganisms are the same ones that have provided these vitamins for generations.
  • The enzymes used by the microorganisms to make the vitamins are the same.

4)     There is no downside to the use of GM organisms as a source of natural vitamins.

    • There is no environmental risk from the use of these GM microorganisms. They don’t contain any dangerous genes that could wreak havoc if they escaped from the food processing plants.
    • Because the purified vitamins are indistinguishable from those obtained from non-GMO sources, there are also no health risks.

5)     The advantage of using these GM organisms is clear. It substantially lowers the cost of vitamins and allows them to be used in the mass market – for example, in popular breakfast cereals.

6)     Most food manufacturers can’t simply use non-GMO sourced vitamins and raise their prices.

    • A recent poll showed that 53% of Americans prefer non-GMO foods, but only 11% are willing to pay more for those foods

What Does the Future Hold?

Even though they are scientifically flawed, the proposed non-GMO labeling laws will probably become the law in several states in the near future. (Good science has never played much of a role in political decisions.)

Currently, there simply aren’t enough non-GMO vitamins available to supply the mass market – even if price were no concern. So, in the short term, many non-GMO processed foods are likely to be less nutritious than the foods they will replace – as we just saw with Grape Nuts and Cheerios.

However, most people feel that American ingenuity and the law of supply and demand will eventually result in a bigger supply of reasonable priced non-GMO vitamins. When that happens non-GMO processed foods will be just as nutritious as the older GM versions.

However, at this point nobody knows how long that will take.

The Bottom Line:

1)     There is a scientific basis for environmental and potential health concerns regarding genetically modified whole foods and the protein extracted from these foods.

2)     However, proposed non-GMO labeling laws would require that a processed food be labeled as genetically modified if it contains any nutrient purified from a genetically modified organism.

3)     There is no scientific justification for this requirement. Purified vitamins from GM and non-GM microorganisms are chemically and biologically indistinguishable. Furthermore, the GM microorganisms used to produce the vitamins pose no environmental or health risks.

4)     Non-GMO vitamins (vitamins prepared from non-GMO microorganisms) are currently in short supply and are very expensive compared to vitamins prepared from GM microorganisms.

5)     Consequently, the unintended consequence of these proposed non-GMO labeling laws will likely be that many of the new non-GMO processed foods will contain fewer vitamins and, therefore, will be less nutritious than the foods they replace – at least in the short term. The new non-GMO Grape Nuts and Cheerios may be just the tip of the iceberg.

These statements have not been evaluated by the Food and Drug Administration. This information is not intended to diagnose, treat, cure or prevent any disease.

Should GMO Labeling Be Required For All Food Ingredients?

Written by Dr. Steve Chaney on . Posted in Environment and Health, Food and Health, Issues

When Is GMO Not GMO?

Author: Dr. Stephen Chaney

GMO-freeI’m probably going to get lots of hate mail for this week’s “Health Tips from the Professor” because I’m finally going to tackle the GMO controversy.

You see, the GMO controversy is very much like Washington politics. On one side of the aisle, you have the people who are absolutely convinced that anything GMO is terrible. On the other side of the aisle, you have people who are absolutely convinced that there are no problems with GMO foods. And both sides are convinced that their opponents have absolutely nothing of intelligence to say on the topic.

So almost anything I say about GMO is bound to offend somebody. But nobody ever accused me of being timid, so let’s get started.

What Are The Health Risks Of Genetically Modified Foods?

I’m going to start with the supposed health risks of GMO foods because that’s my area of greatest expertise, and I’m going to evaluate those health risks from the viewpoint of a card-carrying biochemist. I’ve seen the scary pictures and alarming statements posted on many anti-GMO web sites, but objective evidence that genetically modified foods are harmful to humans is underwhelming at present.

Modifications to DNA And Health Risks

Let’s start at the beginning. Genetic modification occurs in the DNA, and on that basis GMO foods have some potential, but yet unproven, risks. Let me give you an example:

  • Some genetically modified foods carry genes for naturally occurring pesticides so that if bugs try to eat the leaves of those plants they will die.
  • When we eat foods occasionally small pieces of their DNA will find their way into our intestinal track.
  • We have bacteria in our intestinal tracts that excel at picking up small pieces of DNA and inserting them into their genome.
  • So it is theoretically possible that those bacteria might start producing in our intestines the same pesticides produced by the genetically modified foods we ate.

It is an interesting idea, but to my knowledge one that has not yet been shown to have actually occurred in a human being.

Modifications to Proteins And Health Risks

A more likely risk comes from the proteins contained in genetically modified foods:

  • Genetic modifications in the DNA result in the production of modified proteins, so GMO foods, GMO protein powders and foods made from GMO protein sources can be a source of unsuspected food allergies.
  • Unfortunately, food allergies, especially those from genetically modified protein sources, are very difficult to quantify, so we have no good data on how big a problem this actually is.

However, it would be very surprising if there weren’t some individuals with food allergies to genetically modified proteins.

When Is GMO Not GMO?

Many of the GMO opponents take it one step further and want to label as GMO any food or supplement that contains any ingredient made from a genetically modified food. This is where the science is clearly on the other side of the aisle. With respect to purified sugars, purified oils, vitamins and other purified nutrients obtained from foods there is no difference between GMO and non-GMO because these purified nutrients contain neither DNA nor protein.

 Should GMO Labeling Be Required For All Food Ingredients?

For the most part, it isn’t even possible for most manufacturers to produce foods or supplements with all non-GMO ingredients. When the whole GMO issue first entered public awareness the food industry was guided by the science. It made good business sense for them to create a capacity, a pipeline if you will, to make sure that non-GMO protein sources were available to meet the market demand for companies that wanted to make non-GMO protein products for this new GMO-adverse market.

But, nobody anticipated the emotional demand for non-GMO sugars, oils and the like. There was no scientific basis for that demand, so none of the suppliers created the capacity to meet that demand. Currently there is only enough of those kinds of non-GMO ingredients to meet the needs of the bit players in the market. There simply aren’t enough of those ingredients to satisfy the requirements of any manufacturer who deals in the mass market. That, for example, is the reason big players in the market lobbied against the recent California and Washington State propositions that would have required a food product to be labeled GMO if any ingredient in the food was GMO.

Genetically Modified Foods And The Environment

Now that I have managed to alienate almost everyone, I should point out that there are some non-health issues around GMO foods.

  • The biggest issue is that many of the genetically modified foods contain modifications that make them resistant to herbicides, and that encourages overuse of those herbicides with the resultant pollution of air, soil, and water.
  • Another concern is that the increasing reliance on genetically modified food crops is leading to a decrease in the genetic diversity of those crops, which could make them more susceptible to a new virus or pest in the future. This is a theoretical concern, but there is historical precedence for believing that it could happen.
  • Finally, laws that prevent subsistent farmers from saving their own seed for next season’s planting is a major concern in Third World countries. But, that is more an issue of corporate greed than it is of genetic modification.

The Bottom Line:

What is the take-home lesson for you?

From a health perspective:

  • Genetically modified proteins are likely to be a food allergy risk for some people, but we have no good data on how many people are affected by this kind of food allergy
  • Genetically modified DNA is a theoretical concern because of the ability of intestinal bacteria to pick up pieces of DNA, but we have no evidence at present that this has actually ever caused a problem in people.
  • With respect to sugars, oils, and other nutrients extracted from foods it makes no difference whether the food was GMO or non-GMO

From an environmental perspective:

  • Genetic modifications leading to herbicide resistance are a significant environmental concern because it encourages overuse of herbicides.
  • Lack of genetic diversity from the overuse of GMO food crops is a theoretical concern, but one with historical precedence.

These statements have not been evaluated by the Food and Drug Administration. This information is not intended to diagnose, treat, cure or prevent any disease.

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Does Protein Supplement Timing Matter?

Posted May 15, 2018 by Dr. Steve Chaney

How Do You Gain Muscle Mass & Lose Fat Mass?

Author: Dr. Stephen Chaney

 

protein supplement timingMost of what you read about protein supplements on the internet is wrong. That is because most published studies on protein supplements:

  • Are very small
  • Are not double blinded.
    • Both the subjects and the investigators knew who got the protein supplement.
  • Are done by individual companies with their product.
    • You have no idea which ingredients are in their product are responsible for the effects they report.
    • You have no idea how their product compares with other protein products.
    • There is no standardization with respect to the amount or type of protein or the addition of non-protein ingredients.

Because of these limitations there is a lot of misleading information on the benefits of protein supplements timing and maximal benefit. Let’s start by looking at why people use protein supplements. Let’s also look at what is generally accepted as true with respect to the best supplement timing.

There are 4 major reasons people consume protein supplements:

  • Enhance the muscle gain associated with resistance training: In this case, protein supplements are customarily consumed concurrently with the workout.
  • Preserve muscle and accelerate fat loss while on a weight loss diet: In this case, protein supplements are customarily consumed with meals or as meal replacements.
  • Provide a healthier protein source. In this case, protein supplements are customarily consumed with meals in place of meat protein.
  • Prevent muscle loss associated with aging or illness. There is no customary pattern associated with this use of protein supplements.

How good are the data supporting the customary timing of protein supplementation? The answer is: Not very good. The timing is based on a collection of weak studies which do not always agree with each other.

The current study  (J.L. Hudson et al, Nutrition Reviews, 76: 461-468, 2018 ) was designed to fill this void in our knowledge. It is a meta-analysis that compares all reasonably good studies that have looked at the effect of protein supplement timing on weight gain or loss, lean muscle mass gain, fat loss, and the ratio of lean muscle mass to fat mass.

How Was The Study Done?

The authors started by doing a literature search of all studies that met the following criteria:

  • The study was a randomized control trial with parallel design. This means that study contained a control group. It does not mean that the investigators or subjects were blinded with respect to which subjects used a protein supplement and which did not.
  • The subjects were engaged in resistance training.
  • The study lasted 6 weeks or longer.
  • Reliable methods were used to measure body composition (lean muscle mass and fat mass).
  • The subjects were healthy and at least 19 years old.
  • There was no restriction on the food the subjects consumed.

The authors started with 2074 published studies and ended up with 34 that met all their criteria. They then separated the studies into two groups – those in which the protein supplements were used with meals and those in which the protein supplements were used between meals.

Both groups were diverse.

  • Group 1 included subjects who consumed their protein supplement with their meal and those who consumed their protein supplement as a meal replacement.
  • Group 2 included subjects who consumed their protein supplement concurrent with exercise (usually immediately after exercise) and those who consumed their protein supplement at a fixed time of day not associated with exercise.

Does Protein Supplement Timing Matter?

 

protein supplement timing workoutsBecause the individual studies were very diverse in the way they were designed, the authors could not calculate a reliable estimate of how much lean muscle mass was increased or fat mass was decreased. Instead, they calculated the percentage of studies showing an increase in lean muscle mass or a decrease in fat mass.

When the authors compared protein supplements consumed with meals versus protein supplements consumed between meals:

  • Weight gain was observed in 56% of the studies of protein supplementation with meals compared to 72% of the studies of protein supplementation between meals. In other words, protein supplements consumed with meals were less likely to lead to weight gain than protein supplements consumed between meals.
  • An increase in lean muscle mass was observed in 94% of the studies of protein supplementation with meals compared to 90% of the studies of protein supplementation between meals. In other words, timing of protein supplementation did not matter with respect to increase in muscle mass.
  • A loss of fat mass was observed in 87% of the studies of protein supplementation with meals compared to 59% of the studies of protein supplementation between meals. In other words, protein supplements consumed with meals were more likely to lead to loss of fat mass.
  • An increase in the ratio of lean muscle mass to fat mass was observed in 100% of the studies of protein supplementation with meals compared to 87% of the studies of protein supplementation between meals. In short, protein supplements consumed with meals were slightly more likely to lead to an increase in the ratio of lean muscle mass to fat mass.

The following seem to suggest protein supplement timing matters:

The authors pointed out that their findings were consistent with previous studies showing that when protein supplements are consumed with a meal they displace some of the calories that otherwise would have been consumed. Simply put, people naturally compensate by eating less of other foods.

In contrast, the authors stated that previous studies have shown that when foods, especially liquid foods, are consumed as snacks (between meals), people are less likely to compensate by reducing the calories consumed in the next meal.

The others concluded: “Concurrently with resistance training, consuming protein supplements with meals, rather than between meals, may more effectively promote weight control and reduce fat mass without influencing improvements in lean [muscle] mass.”

What Are The Limitations Of The Study?

Meta-analyses such as this one, are only as good as the studies included in the meta-analysis. Unfortunately, most sports nutrition studies are very weak studies. Thus, this meta-analysis is a perfect example of the “Garbage In: Garbage Out (GI:GO)” phenomenon.

For example, let’s start by looking at what the term “protein supplement” meant.

  • Because the studies were done by individual companies with their product, the protein supplements in this meta-analysis:
    • Included whey, casein, soy, bovine colostrum, rice or combinations of protein sources.
    • Were isolates, concentrates, or hydrolysates.
    • Contained various additions like creatine, amino acids, and carbohydrate.
  • As I discuss in my book, Slaying the Food Myths, previous studies have shown that optimal protein and leucine levels are needed to maximize the increase in muscle mass and decrease in fat mass associated with resistance exercise. However, neither protein nor leucine levels were standardized in the protein supplements included in this meta-analysis.
  • Previous studies have shown that protein supplements that have little effect on blood sugar levels (have a low glycemic index) are more likely to curb appetite. However, glycemic index was not standardized for the protein supplements included in this meta-analysis.

protein supplement timing workout peopleIn short, the conclusions of this study might be true for some protein supplements, but not for others. We have no way of knowing.

We also need to consider the composition of the two groups.

  • Protein supplements used as meal replacements are more likely to decrease weight and fat mass than protein supplements consumed with meals. Yet, both were included in group 1.
  • Some studies suggest that protein supplements consumed concurrent with resistance exercise are more likely to increase muscle mass than protein supplements consumed another time of day. Yet, both are included in group 2. We also have no idea whether the meals with protein supplements in group 1 were consumed shortly after exercise or at an entirely different time of day.

This was the most glaring weakness of the study because it was completely avoidable. The authors could have grouped the studies into categories that made more sense.

In other words, there are multiple weaknesses that limit the predictive power of this study.

What Can We Learn From This Study?

Despite its many limitations, this study does remind us that protein supplements do have calories. This is of relatively little importance for people whose primary goal is to increase lean muscle mass.

However, most of us are using protein supplements to lose weight or to increase our lean mass to fat mass ratio. Simply put, we are either trying to lean out (shape up) or lose weight. And, we want to lose that weight primarily by getting rid of excess fat. For us, calories do matter. With that in mind:

  • If we are consuming a protein supplement immediately after exercise or between meals we probably should make a conscious effort to reduce our daily caloric intake elsewhere in our diet.
  • Alternatively, we could consume the protein supplement with a meal, but time the meal so it occurs shortly after exercise.

 

The Bottom Line:

 

A recent study looked at the optimal timing of protein supplements consumed by subjects who were engaged in resistance exercise. Specifically, the study compared protein supplements consumed with meals versus protein supplements consumed between meals on weight, lean muscle mass, fat mass, and the ratio of lean muscle mass to fat mass. The study reported:

  • Protein supplements consumed with meals were less likely to lead to weight gain than protein supplements consumed between meals.
  • Timing of protein supplementation did not matter with respect to increase in muscle mass.
  • Protein supplements consumed with meals were more likely to lead to loss of fat mass.
  • Protein supplements consumed with meals were slightly more likely to lead to an increase in the ratio of lean mass to fat mass.

The authors pointed out that their findings were consistent with previous studies showing that when a protein supplement was consumed with a meal it displaces some of the calories that would have been otherwise consumed. Simply put, people naturally compensate by eating less of other foods.

In contrast, the authors said that previous studies have shown that when foods, especially liquid foods, are consumed as snacks (between meals), people are less likely to compensate by reducing the calories consumed in the next meal.

As discussed in the article above, the study has major weaknesses. However, despite its many weaknesses, this study does remind us that protein supplements do have calories. This is of relatively little importance for people whose primary goal is to increase lean muscle mass.

However, for those of us who are using protein supplements to lose weight or to increase our lean mass to fat mass ratio, calories do matter.  With that in mind:

  • If we are consuming a protein supplement immediately after exercise or between meals we probably should make a conscious effort to reduce our daily caloric intake elsewhere in our diet.
  • Alternatively, we could consume the protein supplement with a meal, but time the meal so it occurs shortly after exercise.

For more details, read the article above:

 

These statements have not been evaluated by the Food and Drug Administration. This information is not intended to diagnose, treat, cure or prevent any disease.

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