The Dirty Dozen

Written by Dr. Steve Chaney on . Posted in Environment and Health, Issues

Environmental Toxins That Affect Brain Development

 Author: Dr. Stephen Chaney

 In a recent review, Drs. Grandjean and Landrigan (The Lancet Neurology, 13: 330-338, 2014) identified 12 toxic chemicals which are abundant in our environment and are developmental neurotoxins.

These are all chemicals that damage brain development. They can cause decreases in IQ and aggressive or hyperactive behavior in children – and that those changes may be permanent.

Let’s look at these developmental neurotoxins and where they are found.

The Dirty Dozen

In their review Grandjean & Landrigan identified 6 developmental neurotoxins that were known in 2006, and 6 more chemicals that have been confirmed to be developmental neurotoxins between 2006 and 2023.

Developmental Neurotoxins Known in 2006 and their sources:

  • Lead
    • Main Sources: paint, gasoline, solder and consumer products such as toys & jewelry
    • Current status: Lead has been banned in paint since 1978 and from gasoline since 1996. Millions of houses still contain lead paint. Other current sources are inexpensive toys and costume jewelry imported from China and other countries without tight regulations.
    • The EPA estimates that 1 million children in the US are affected by elevated lead levels.
  • Methylmercury
    • Main Sources: discharges into air & water from coal-burning power plants, mining, pulp & paper industries.
  • Polychorinated biphenyls (PCBs)
    • Main Sources: transformers and many commercial products
    • Current status: Banned in 1979, but continues to be a common environmental contaminant because this group of chemicals is very long-lived.
  • Arsenic:
    • Main Sources: extraction of metals from rock (smelting), algaecides, herbicides, pesticides and pressure-treated wood.
    • Current status: Pressure treated wood banned in 2003 for residential use. Still found in some playgrounds and older buildings.
  • Toluene:
    • Main Sources: gasoline. It is also a solvent for paints, paint thinners, spot removers, adhesives, antifreeze, & some consumer products like fingernail polish removers.
    • Current status: Common in consumer products. Read labels and make sure windows are open if you use.

Developmental Neurotoxins Identified Since 2006 and their sources:

  • Manganese
    • Main Sources: municipal wastewater discharge, emissions generated during alloy, steel & iron production, emissions from burning of fuel additives
  • Flouride
    • Main Sources: naturally elevated in groundwater in certain regions, added to municipal water supply, most bottled beverages and toothpaste.
    • The American Academy of Pediatrics has warned that children drinking fluoridated water, fluoridated beverages, using fluoridated toothpaste and receiving fluoride treatments for their teeth may be receiving excess fluoride.
  • Chlorpyrifos
    • Main Sources: insecticide
    • Current status: Banned for use in homes in 2001. Still one of the most widely used insecticides in agriculture.
  • DDT
    • Main Sources: insecticide
    • Current status: Banned for use in this country in 1972. DDT and its breakdown products still found in our water supply. DDT still in use in agriculture and insect control in some countries.
  • Trichloroethylene (TCE)
    • Main Sources: widely used in dry cleaning fabrics, the textile industry and metal degreasing
    • Current status: Found in groundwater due to discharge from factories and dry cleaners.
  • Polybrominated diphenyl ethers (PBDEs)
    • Main Sources: flame retardants – used in building materials, electronics, mattresses & household furniture, plastics, polyurethane foams & textiles.
    • Current status: Readily leached into the environment. Found in dust, water, food & human breast milk

These statements have not been evaluated by the Food and Drug Administration. This information is not intended to diagnose, treat, cure or prevent any disease.

 

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High Protein Diets and Weight Loss

Posted October 16, 2018 by Dr. Steve Chaney

Do High Protein Diets Reduce Fat And Preserve Muscle?

Author: Dr. Stephen Chaney

Healthy Diet food group, proteins, include meat (chicken or turkAre high protein diets your secret to healthy weight loss? There are lots of diets out there – high fat, low fat, Paleolithic, blood type, exotic juices, magic pills and potions. But recently, high protein diets are getting a lot of press. The word is that they preserve muscle mass and preferentially decrease fat mass.

If high protein diets actually did that, it would be huge because:

  • It’s the fat – not the pounds – that causes most of the health problems.
  • Muscle burns more calories than fat, so preserving muscle mass helps keep your metabolic rate high without dangerous herbs or stimulants – and keeping your metabolic rate high helps prevent both the plateau and yo-yo (weight regain) characteristic of so many diets.
  • When you lose fat and retain muscle you are reshaping your body – and that’s why most people are dieting to begin with.

So let’s look more carefully at the recent study that has been generating all the headlines (Pasiakos et al, The FASEB Journal, 27: 3837-3847, 2013).

The Study Design:

This was a randomized control study with 39 young (21), healthy and fit men and women who were only borderline overweight (BMI = 25). These volunteers were put on a 21 day weight loss program in which calories were reduced by 30% and exercise was increased by 10%. They were divided into 3 groups:

  • One group was assigned a diet containing the RDA for protein (about 14% of calories in this study design).
  • The second group’s diet contained 2X the RDA for protein (28% of calories)
  • The third group’s diet contained 3X the RDA for protein (42% of calories)

In the RDA protein group carbohydrate was 56% of calories, and fat was 30% of calories. In the other two groups the carbohydrate and fat content of the diets was decreased proportionally.

Feet_On_ScaleWhat Did The Study Show?

  • Weight loss (7 pounds in 21 days) was the same on all 3 diets.
  • The high protein (28% and 42%) diets caused almost 2X more fat loss (5 pounds versus 2.8 pounds) than the diet supplying the RDA amount of protein.
  • The high protein (28% and 42%) diets caused 2X less muscle loss (2.1 pounds versus 4.2 pounds) than the diet supplying the RDA amount of protein.
  • In case you didn’t notice, there was no difference in overall results between the 28% (2X the RDA) and 42% (3X the RDA) diets.

Pros And Cons Of The Study:

  • The con is fairly obvious. The participants in this study were all young, healthy and were not seriously overweight. If this were the only study of this type one might seriously question whether the results were applicable to middle aged, overweight coach potatoes. However, there have been several other studies with older, more overweight volunteers that have come to the same conclusion – namely that high protein diets preserve muscle mass and enhance fat loss.
  • The value of this study is that it defines for the first time the upper limit for how much protein is required to preserve muscle mass in a weight loss regimen. 28% of calories is sufficient, and there appear to be no benefit from increasing protein further. I would add the caveat that there are studies suggesting that protein requirements for preserving muscle mass may be greater in adults 50 and older.

The Bottom Line:

1)    Forget the high fat diets, low fat diets, pills and potions. High protein diets (~2X the RDA or 28% of calories) do appear to be the safest, most effective way to preserve muscle mass and enhance fat loss in a weight loss regimen.

2)     That’s not a lot of protein, by the way. The average American consumes almost 2X the RDA for protein on a daily basis. However, it is significantly more protein than the average American consumes when they are trying to lose weight. Salads and carrot sticks are great diet foods, but they don’t contain much protein.

3)     Higher protein intake does not appear to offer any additional benefit – at least in young adults.

4)     Not all high protein diets are created equal. What some people call high protein diets are laden with saturated fats or devoid of carbohydrate. The diet in this study, which is what I recommend, had 43% healthy carbohydrates and 30% healthy fats.

5)    These diets were designed to give 7 pounds of weight loss in 21 days – which is what the experts recommend. There are diets out there promising faster weight loss but they severely restrict calories and/or rely heavily on stimulants, they do not preserve muscle mass, and they often are not safe. In addition they are usually temporary.  I do not recommend them.

6)    This level of protein intake is safe for almost everyone. The major exception would be people with kidney disease, who should always check with their doctor before increasing protein intake. The only other caveat is that protein metabolism creates a lot of nitrogenous waste, so you should drink plenty of water to flush that waste out of your system. But, water is always a good idea.

7)     The high protein diets minimized, but did not completely prevent, muscle loss. Other studies suggest that adding the amino acid leucine to a high protein diet can give 100% retention of muscle mass in a weight loss regimen – but that’s another story for another day.

These statements have not been evaluated by the Food and Drug Administration. This information is not intended to diagnose, treat, cure or prevent any disease.

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